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Striving for a cancer-free future

CEC Publications 2013

Breast Cancer

Bassett JK, Baglietto L, Hodge AM, Severi G, Hopper JL, English DR, Giles GG. Dietary intake of B vitamins and methionine and breast cancer riskCancer Causes Control. 2013;24:1555-63

Dite GS, Mahmoodi M, Bickerstaffe A, Hammet F, Macinnis RJ, Tsimiklis H, Dowty JG, Apicella C, Phillips KA, Giles GG, Southey MC, Hopper JL. Using snp genotypes to improve the discrimination of a simple breast cancer risk prediction modelBreast Cancer Res Treat. 2013;139:887-896

French JD, Ghoussaini M, Edwards SL, et al. Functional variants at the 11q13 risk locus for breast cancer regulate cyclin d1 expression through long-range enhancersAm J Hum Genet. 2013;92:489-503 

Garcia-Closas M, Couch FJ, Lindstrom S, et al. Genome-wide association studies identify four er negative-specific breast cancer risk lociNat Genet. 2013;45:392-398 

Gaudet MM, Kuchenbaecker KB, Vijai J, etal. Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer riskPLoS Genet. 2013;9:e1003173

John EM, McGuire V, Thomas DC, Haile R, Ozcelik H, Milne RL, Felberg A, West DW, Miron A, Knight JA, Terry MB, Daly M, Buys SS, Andrulis IL, Hopper JL, Southey MC, Giles GG, Apicella C, Thorne H, Whittemore AS. Diagnostic chest x-rays and breast cancer risk before age 50 years for BRCA1 and BRCA2 mutation carriers. Cancer Epidemiol Biomarkers Prev. 2013;22:1547-1556

Jung S, Spiegelman D, Baglietto L, et al. Fruit and vegetable intake and risk of breast cancer by hormone receptor statusJ Natl Cancer Inst. 2013;105:219-236 

Krishnan K, Bassett JK, Macinnis RJ, English DR, Hopper JL, McLean CA, Giles GG, Baglietto L.Associations between weight in early adulthood, change in weight and breast cancer risk in postmenopausal womenCancer Epidemiol Biomarkers Prev. 2013;22:1409-1416

Macinnis RJ, Bickerstaffe A, Apicella C, Dite GS, Dowty JG, Aujard K, Phillips KA, Weideman P, Lee A, Terry MB, Giles GG, Southey MC, Antoniou AC, Hopper JL. Prospective validation of the breast cancer risk prediction model boadicea and a batch-mode version boadiceacentre. Br J Cancer. 2013;100:1296-1301

Meyer KB, O'Reilly M, Michailidou K, et al. Fine-scale mapping of the FGFR2 breast cancer risk locus: Putative functional variants differentially bind FOXA1 and E2F1Am J Hum Genet. 2013;93:1046-1060 

Michailidou K, Hall P, Gonzalez-Neira A, et al. Large-scale genotyping identifies 41 new loci associated with breast cancer riskNat Genet. 2013;45:353-361 

Muller DC, Baglietto L, Manning JT, McLean C, Hopper JL, English DR, Giles GG, Severi G. Reply to comment on: 'Second to fourth digit ratio (2d:4d), breast cancer risk factors, and breast cancer risk: A prospective cohort study'Br J Cancer. 2013;108:743 

Nguyen TL, Schmidt DF, Makalic E, Dite GS, Stone J, Apicella C, Bui M, Macinnis RJ, Odefrey F, Cawson J, Treloar SA, Southey MC, Giles GG, Hopper JL. Explaining variance in the cumulus mammographic measures that predict breast cancer risk: A twins and sisters studyCancer Epidemiol Biomarkers Prev. 2013;22:2395-2403  

Nguyen-Dumont T, Teo ZL, Pope BJ, Hammet F, Mahmoodi M, Tsimiklis H, Sabbaghian N, Tischkowitz M, Foulkes WD, Giles GG, Hopper JL, Southey MC, Park DJ. Hi-plex for high-throughput mutation screening: Application to the breast cancer susceptibility gene PALB2 . BMC Med Genomics. 2013;6:48 

Nickels S, Truong T, Hein R, Stevens K, et al. Evidence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factorsPLoS Genet. 2013;9:e1003284 

Nickson C, Arzhaeva Y, Aitken Z, Elgindy T, Buckley M, Li M, English DR, Kavanagh AM. Autodensity: An automated method to measure mammographic breast density that predicts breast cancer risk and screening outcomesBreast Cancer Res. 2013;15:R80

Obazee O, Justenhoven C, Winter S, Chang-Claude J, Rudolph A, Seibold P, Flesch-Janys D, Hannelius U, Li J, Humphreys K, Hall P, Giles G, Severi G, Baglietto L, Southey M, Rabstein S, Harth V, Lotz A, Pesch B, Bruning T, Baisch C, Ko YD, Hamann U, Brauch H. Confirmation of the reduction of hormone replacement therapy-related breast cancer risk for carriers of the hsd17b1_937_g variantBreast Cancer Res Treat. 2013;138:543-548 

Purrington KS, Slager S, Eccles D, Yannoukakos D, et al. Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple negative breast cancer . Carcinogenesis. 2013

Rudolph A, Hein R, Lindstrom S, et al. Genetic modifiers of menopausal hormone replacement therapy and breast cancer risk: A genome-wide interaction studyEndocrine-related cancer. 2013

Teo ZL, Provenzano E, Dite GS, Park DJ, et al. Tumour morphology predicts PALB2 germline mutation status. Br J Cancer. 2013;109:154-163

Ovarian Cancer

Permuth-Wey J, Lawrenson K, Shen HC, et al. Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31Nature communications. 2013;4:1627 

Pharoah PD, Tsai YY, Ramus SJ, et al. Gwas meta-analysis and replication identifies three new susceptibility loci for ovarian cancerNat Genet. 2013;45:362-370 

Shen H, Fridley BL, Song H, et al. Epigenetic analysis leads to identification of HHF1B as a subtype-specific susceptibility gene for ovarian cancerNature communications. 2013;4:1628 

Breast and Ovarian Cancer

Bojesen SE, Pooley KA, Johnatty SE, et al. Multiple independent variants at the tert locus are associated with telomere length and risks of breast and ovarian cancerNat Genet. 2013;45:371-384 

Colorectal Cancer

Akbari MR, Anderson LN, Buchanan DD, Clendenning M, Jenkins MA, Win AK, Hopper JL, Giles GG, Nam R, Narod S, Gallinger S, Cleary SP. Germline HOXB13 p.Gly84glu mutation and risk of colorectal cancerCancer Epidemiol. 2013;37:424-427 

Bassett JK, Severi G, Hodge AM, Baglietto L, Hopper JL, English DR, Giles GG. Dietary intake of B vitamins and methionine and colorectal cancer risk. Nutrition and cancer. 2013;65:659-667

Buchanan DD, Win AK, Walsh MD, Walters RJ, Clendenning M, Nagler BN, Pearson SA, Macrae F, Parry S, Arnold J, Winship I, Giles GG, Lindor NM, Potter JD, Hopper JL, Rosty C, Young JP, Jenkins MA. Family history of colorectal cancer in braf p.V600e mutated colorectal cancer casesCancer Epidemiol Biomarkers Prev. 2013;2013;22:917-926

Dowty JG, Win AK, Buchanan DD, Lindor NM, Macrae FA, Clendenning M, Antill YC, Thibodeau SN, Casey G, Gallinger S, Marchand LL, Newcomb PA, Haile RW, Young GP, James PA, Giles GG, Gunawardena SR, Leggett BA, Gattas M, Boussioutas A, Ahnen DJ, Baron JA, Parry S, Goldblatt J, Young JP, Hopper JL, Jenkins MA. Cancer risks for MLH1 and MSH2 mutation carriersHum Mutat. 2013;34:490-497 

Morrison DS, Parr CL, Lam TH, Ueshima H, Kim HC, Jee SH, Murakami Y, Giles G, Fang X, Barzi F, Batty GD, Huxley RR, Woodward M. Behavioural and metabolic risk factors for mortality from colon and rectum cancer: Analysis of data from the asia- pacific cohort studies collaborationAsian Pac J Cancer Prev. 2013;14:1083-1087

Rosty C, Young JP, Walsh MD, Clendenning M, Walters RJ, Pearson S, Pavluk E, Nagler B, Pakenas D, Jass JR, Jenkins MA, Win AK, Southey MC, Parry S, Hopper JL, Giles GG, Williamson E, English DR, Buchanan DD. Colorectal carcinomas with kras mutation are associated with distinctive morphological and molecular featuresModern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2013;26:825-834 

Rosty C, Young JP, Walsh MD, Clendenning M, Sanderson K, Walters RJ, Parry S, Jenkins MA, Win AK, Southey MC, Hopper JL, Giles GG, Williamson EJ, English DR, Buchanan DD. PIK3ca activating mutation in colorectal carcinoma: Associations with molecular features and survival. PLoS One. 2013;8:e65479

Walsh MD, Clendenning M, Williamson E, Pearson SA, Walters RJ, Nagler B, Packenas D, Win AK, Hopper JL, Jenkins MA, Haydon AM, Rosty C, English DR, Giles GG, McGuckin MA, Young JP, Buchanan DD. Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CPG island methylator phenotype. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2013;26:1642-1656

Walters RJ, Williamson EJ, English DR, Young JP, Rosty C, Clendenning M, Walsh MD, Parry S, Ahnen DJ, Baron JA, Win AK, Giles GG, Hopper JL, Jenkins MA, Buchanan DD. Association between hypermethylation of DNA repetitive elements in white blood cell DNA and early-onset colorectal cancer. Epigenetics : official journal of the DNA Methylation Society. 2013;8:748-7 

Win AK, Hopper JL, Buchanan DD, Young JP, Tenesa A, Dowty JG, Giles GG, Goldblatt J, Winship I, Boussioutas A, Young GP, Parry S, Baron JA, Duggan D, Gallinger S, Newcomb PA, Haile RW, Marchand LL, Lindor NM, Jenkins MA. Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers? Eur J Cancer. 2013 

Win AK, Lindor NM, Winship I, Tucker KM, Buchanan DD, Young JP, Rosty C, Leggett B, Giles GG, Goldblatt J, Macrae FA, Parry S, Kalady MF, Baron JA, Ahnen DJ, Marchand LL, Gallinger S, Haile RW, Newcomb PA, Hopper JL, Jenkins MA. Risks of colorectal and other cancers after endometrial cancer for women with lynch syndromeJ Natl Cancer Inst. 2013;105:274-279 

Prostate Cancer

Amin Al Olama A, Kote-Jarai Z, Schumacher FR, et al. A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive diseaseHum Mol Genet. 2013;22:408-415 

Bassett JK, Severi G, Hodge AM, Macinnis RJ, Gibson RA, Hopper JL, English DR, Giles GG. Plasma phospholipid fatty acids, dietary fatty acids and prostate cancer riskInt J Cancer. 2013;133:1882-1891

Eeles RA, Olama AA, Benlloch S, et al. Identification of 23 new prostate cancer susceptibility loci using the  ICOGS custom genotyping arrayNat Genet. 2013;45:385-391 

Evans SM, Millar JL, Wood JM, Davis ID, Bolton D, Giles GG, Frydenberg M, Frauman A, Costello A, McNeil JJ. The prostate cancer registry: Monitoring patterns and quality of care for men diagnosed with prostate cancerBJU Int. 2013;111:E158-166 

Evans SM, Millar JL, Davis ID, Murphy DG, Bolton DM, Giles GG, Frydenberg M, Andrianopoulos N, Wood JM, Frauman AG, Costello AJ, McNeil JJ. Patterns of care for men diagnosed with prostate cancer in victoria from 2008 to 2011. Med J Aust. 2013;198:540-545

Evans SM, Millar JL, Frydenberg M, Murphy DG, Davis ID, Spelman T, Bolton DM, Giles GG, Dean J, Costello AJ, Frauman AG, Kearns PA, Day L, Daniels C, McNeil JJ. Positive surgical margins: Rate, contributing factors and impact on further treatment: Findings from the prostate cancer registryBJU Int. 2013

Kote-Jarai Z, Saunders EJ, Leongamornlert DA, et al. Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with tert expressionHum Mol Genet. 2013;22:2520-2528 

Macinnis RJ, Severi G, Baglietto L, Dowty JG, Jenkins MA, Southey MC, Hopper JL, Giles GG. Population-based estimate of prostate cancer risk for carriers of the HOXB13 missense mutation G84EPLoS One. 2013;8:e54727 

Muhlbradt E, Ma J, Severi G, Ortner E, Hayes V, Hoang HN, Stampfer M, Giles G, Pollak M, Gelmann EP. Variant NKX3.1 and serum IGF-1: Investigation of interaction in prostate cancer . Genes & cancer. 2013;4:535-545

Muller DC, Giles GG, Sinclair R, Hopper JL, English DR, Severi G. Age-dependent associations between androgenetic alopecia and prostate cancer riskCancer Epidemiol Biomarkers Prev. 2013;22:209-215 

Orozco G, Goh CL, Al Olama AA, Benlloch-Garcia S, Govindasami K, Guy M, Muir KR, Giles GG, Severi G, Neal DE, Hamdy FC, Donovan JL, Kote-Jarai Z, Easton DF, Eyre S, Eeles RA. Common genetic variants associated with disease from genome-wide association studies are mutually exclusive in prostate cancer and rheumatoid arthritis. BJU Int. 2013;111:1148-1155

Teerlink CC, Thibodeau SN, McDonnell SK, et al. Association analysis of 9,560 prostate cancer cases from the international consortium of prostate cancer genetics confirms the role of reported prostate cancer associated snps for familial diseaseHum Genet. 2013 

Xu J, Lange EM, Lu L, Zheng SL, et al. Hoxb13 is a susceptibility gene for prostate cancer: Results from the international consortium for prostate cancer genetics (ICPCG)Hum Genet. 2013;132:5-14

Yu OH, Foulkes WD, Dastani Z, Martin RM, Eeles R, Consortium P, Investigators CG, Richards JB. An assessment of the shared allelic architecture between type II diabetes and prostate cancerCancer Epidemiol Biomarkers Prev. 2013;22:1473-1475

Lung Cancer

Ball D, Thursfield V, Irving L, Mitchell P, Richardson G, Torn-Broers Y, Wright G, Giles G. Evaluation of the simplified comorbidity score (colinet) as a prognostic indicator for patients with lung cancer: A cancer registry studyLung cancer. 2013 

Mitchell PL, Thursfield VJ, Ball DL, Richardson GE, Irving LB, Torn-Broers Y, Giles GG, Wright GM. Lung cancer in Victoria: Are we making progress? Med J Aust. 2013;199:674-679  

Melanoma

Cust AE, Goumas C, Vuong K, Davies JR, Barrett JH, Holland EA, Schmid H, Agha-Hamilton C, Armstrong BK, Kefford RF, Aitken JF, Giles GG, Bishop D, Newton-Bishop JA, Hopper JL, Mann GJ, Jenkins MA. MC1R genotype as a predictor of early-onset melanoma, compared with self-reported and physician-measured traditional risk factors: An australian case-control-family studyBMC Cancer. 2013;13:406

Other Cancers

Berndt SI, Skibola CF, Joseph V, et al. Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemiaNat Genet. 2013;45:868-876

Coory M, White VM, Johnson KS, Hill DJ, Jefford M, Harrison S, Winship I, Millar J, Giles GG. Systematic review of quality improvement interventions directed at cancer specialistsJ Clin Oncol. 2013;31:1583-1591 

Earp MA, Kelemen LE, Magliocco AM, Ovarian Cancer Association Consortium et al. Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA . Hum Genet. 2013

Mathews JD, Forsythe AV, Brady Z, Butler MW, Goergen SK, Byrnes GB, Giles GG, Wallace AB, Anderson PR, Guiver TA, McGale P, Cain TM, Dowty JG, Bickerstaffe AC, Darby SC. Cancer risk in 680,000 people exposed to computed tomography scans in childhood or adolescence: Data linkage study of 11 million australians. BMJ. 2013;346:f2360

Ta AD, Bolton DM, Dimech MK, White V, Davis ID, Coory M, Millar J, Giles G. Contemporary management of renal cell carcinoma (RCC) in victoria: Implications for longer term outcomes and costs . BJU Int. 2013;112 Suppl 2:36-43

Wong Doo N, Coory M, White V, Harrison SJ, Prince HM, Millar JL, Dimech M, Giles GG, Project I. Low uptake of upfront autologous transplantation for myeloma in a jurisdiction with universal health care coverage: A population-based patterns of care study in Australia . Clinical lymphoma, myeloma & leukemia. 2013 

Other Conditions

Aung KZ, Makeyeva G, Adams MK, Chong EW, Busija L, Giles GG, English DR, Hopper J, Baird PN, Guymer RH, Robman LD. The prevalence and risk factors of epiretinal membranes: The Melbourne Collaborative Cohort StudyRetina. 2013;33:1026-1034 

Bui D, Burgess J, Matheson M, Erbas B, Perret J, Morrison S, Giles G, Hopper J, Thomas P, Markos J, Abramson M, Walters EH, Dharmage S. Ambient wood smoke, traffic pollution and adult asthma prevalence and severityRespirology. 2013

Global Burden of Metabolic Risk Factors for Chronic Diseases Collaboration, The (BMI Mediated Effects). Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: A pooled analysis of 97 prospective cohorts with 1·8 million participants . The Lancet. 2013 

Hodge A, Almeida OP, English DR, Giles GG, Flicker L. Patterns of dietary intake and psychological distress in older australians: Benefits not just from a mediterranean dietInternational psychogeriatrics / IPA. 2013;25:456-466 

Hodge AM, Flicker L, O'Dea K, English DR, Giles GG. Diabetes and ageing in the Melbourne Collaborative Cohort Study (MCCS)Diabetes Res Clin Pract. 2013;100:398-403

Hodge AM, English DR, Giles GG, Flicker L. Social connectedness and predictors of successful ageingMaturitas. 2013;75:361-366

Hyun KK, Huxley RR, Arima H, Woo J, Lam TH, Ueshima H, Fang X, Peters SA, Jee SH, Giles GG, Barzi F, Woodward M. A comparative analysis of risk factors and stroke risk for asian and non-asian men: The Asia Pacific Cohort Sudies CollaborationInternational journal of stroke : official journal of the International Stroke Society. 2013;8:606-611

Kandane-Rathnayake RK, Tang ML, Simpson JA, Burgess JA, Meszaros D, Feather I, Southey MC, Schroen CJ, Hopper J, Morrison SC, Giles GG, Walters EH, Dharmage SC, Matheson MC. Adult serum cytokine concentrations and the persistence of asthma. International archives of allergy and immunology. 2013;161:342-350

Mishra GD, Anderson D, Schoenaker DA, Adami HO, Avis NE, Brown D, Bruinsma F, Brunner E, Cade JE, Crawford SL, Dobson AJ, Elliott J, Giles GG, Gold EB, Hayashi K, Kuh D, Lee KA, Lee JS, Melby MK, Mizunuma H, Sievert LL, Weiderpass E. Interlace: A new international collaboration for a life course approach to women's reproductive health and chronic disease eventsMaturitas. 2013;74:235-240 

Muller DC, Manning JT, Hopper JL, English DR, Giles GG, Severi G. No strong association between second to fourth digit ratio (2d:4d) and adult anthropometric measures with emphasis on adiposityAnnals of human biology. 2013;40:201-204 

Oktaria V, Dharmage SC, Burgess JA, Simpson JA, Morrison S, Giles GG, Abramson MJ, Walters EH, Matheson MC. Association between latitude and allergic diseases: A longitudinal study from childhood to middle-ageAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2013;110:80-85 e81 

Perret JL, Dharmage SC, Matheson MC, Johns DP, Gurrin LC, Burgess JA, Marrone J, Markos J, Morrison S, Feather I, Thomas PS, McDonald CF, Giles GG, Hopper JL, Wood-Baker R, Abramson MJ, Walters EH. The interplay between the effects of lifetime asthma, smoking, and atopy on fixed airflow obstruction in middle ageAmerican journal of respiratory and critical care medicine. 2013;187:42-48 

Sinclair RD, English DR, Giles GG. Are bald men more virile than their well thatched contemporaries? Med J Aust. 2013;199:811-812

Turner MC, Krewski D, Armstrong BK, Chetrit A, Giles GG, Hours M, McBride ML, Parent ME, Sadetzki S, Siemiatycki J, Woodward A, Cardis E. Allergy and brain tumors in the interphone study: Pooled results from Australia, Canada, France, Israel, and New ZealandCancer Causes Control. 2013;24:949-960

van Leeuwen MT, Turner JJ, Falster MO, Meagher NS, Joske DJ, Grulich AE, Giles GG, Vajdic CM. Latitude gradients for lymphoid neoplasm subtypes in Australia support an association with ultraviolet radiation exposureInt J Cancer. 2013;133:944-951 

Wang Y, Wluka AE, Simpson JA, Giles GG, Graves SE, de Steiger RN, Cicuttini FM. Body weight at early and middle adulthood, weight gain and persistent overweight from early adulthood are predictors of the risk of total knee and hip replacement for osteoarthritisRheumatology (Oxford). 2013;82:1033-1041 

Scientific Methods

Joo JE, Wong EM, Baglietto L, Jung CH, Tsimiklis H, Park DJ, Wong NC, English DR, Hopper JL, Severi G, Giles GG, Southey MC. The use of DNA from archival dried blood spots with the infinium humanmethylation450 arrayBMC biotechnology. 2013;13:23 

Karahalios A, Baglietto L, Lee KJ, English DR, Carlin JB, Simpson JA. The impact of missing data on analyses of a time-dependent exposure in a longitudinal cohort: A simulation studyEmerging themes in epidemiology. 2013;10:6-16