Dr Christine Hawkins, A/Prof David Curtis, Dr Elizabeth Algar
La Trobe University
Some new classes of anti-cancer drugs, which are currently being developed and evaluated, directly activate self-destruction pathways within tumour cells, rather than indirectly killing cancer cells via damaging their DNA.
This project explores the exciting possibility that these new agents may be less likely than DNA-damaging chemotherapy or radiotherapy to trigger development of subsequent cancers in patients cured of their original malignancy.
Lay Report - Final
Are direct apoptosis inducers less mutagenic than chemotherapy drugs?
Cancer Council Research Grant
$98,725 pa (2012 & 2013), $100,000 (2014)