Structural linkage between ligand discrimination and receptor activation by interleukin-3

Lead researcher

Dr Urmi Dhagat, Dr Sophie Broughton, Prof Michael Parker, A/Prof Louise Purton


Structural Biology, St Vincent's Institute of Medical Research

Years funded


This project studies the mechanism by which interleukin-3 activates abnormal signalling in leukaemic cells. Our findings will allow development of new approaches by which we could specifically target and disrupt leukaemic cell survival.

Funding Body

Cancer Council Research Grant


$99,599 in 2017, $99,199 in 2018 and $99,199 in 2019