Natural molecules that prevent cancer

Project Description

The immune system naturally detects and destroys tumour cells as they develop and effectively mobilizing the immune system offers a new and promising strategy for treating cancer patients. When the immune system fails to eliminate tumour cells it is often because they have developed mutations that provide a selective survival advantage. We wish to characterize the major mechanisms by which tumour cells evade a key killing pathway that white blood lymphocytes use to eliminate tumour cells and then design better therapies.  

Lay report: Natural molecules that prevent cancer

Scientific Description

TRAIL-mediated immunosurveillance, immunoselection and immunotherapy of cancer

Year

2005-2007

Researchers

A/Prof Mark Smyth

Institution

Peter MacCallum Cancer Centre

Award / Duration

Duration: 2005-2007

Funding

$70,000 per annum for 3 years

TRAIL-mediated immunosurveillance, immunoselection and immunotherapy of cancer
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