Cancer research FAQs

How much research do we fund annually?

What is the difference between research done at the Cancer Council’s headquarters and research done in other institutions?

What is the Cancer Council’s strategy for cancer research?

How is cancer research coordinated worldwide?

Where does the money come from?

Where is the money used?

Who selects and monitors Cancer Council research?

How do scientists talk to each other about cancer research?

How do you know when research is real science?

What is ‘evidence-based’?

How is research organised and funded in Australia?

What is a conflict of interest in cancer research?

 

How much research do we fund annually?

The Cancer Council spends around $19 million on research in Victoria each year.

This table shows our research expenditure over the last three years. Except for the amounts provided through our Medical and Scientific Committee, the amounts below include money provided directly to our inhouse researchers plus money they win in competition from external agencies such as the National Health and Medical Research Council and US National Institutes of Health.

Research

$000s
2004

$000s
2005

$000s
2006

Support of basic scientific studies and programs funded by the Medical and Scientific Committee, clinical investigations and programs $5067 $6259 $8644
Victorian Cancer Registry—registers all cancer cases in Victoria and provides statistical analyses $1682 $1622 $1904
Centre for Behavioural Research in Cancer—a centre for research into behavioural aspects of cancer prevention, detection and rehabilitation $2407 $3183 $2987
Cancer Epidemiology Centre—a centre for research into the occurrence, distribution and determinants of disease $3399 $3775 $3857
Health 2000—a study to ascertain the effect of lifestyle factors (especially diet) on the incidence of a range of diseases. $570 $1290 $567
VicHealth Centre for Tobacco Control—a centre to investigate new ways to reduce tobacco usage $1316 $1635 $1867
Total research $14,441 $17,764 $19,826

 

More information about our research can be found in our Annual Review.

More information about our income and expenditure is in our annual report to parliament.


What is the difference between research done at the Cancer Council’s headquarters and research done in other institutions?

The fields of research differ. In response to a lack of epidemiological and behavioural research in cancer in Victoria, in the 1980s the Cancer Council decided it needed to develop these fields by setting up two new research centres, the Cancer Epidemiology Centre and the Centre for Behavioural Research in Cancer. It has continued to fund these ‘inhouse’ groups at our Carlton HQ, and they now attract substantial additional research support from other agencies. All other fields of research are supported in universities, institutes and hospitals through a competitive grant scheme funded by the Cancer Council.

What is the Cancer Council’s strategy for cancer research?

One of the four basic strategies of The Cancer Council Victoria is to ‘Build the Knowledge Base for Cancer Control’. Hence, we invest in research along the whole spectrum of cancer control from studies designed to:

  • funcover underlying causes at a cellular level
  • describe and interpret patterns of occurrence at a population level using epidemiological methods
  • test ways to prevent cancer developing (including behavioural change)
  • investigate, diagnose and screen for cancer
  • test drugs and other treatments (including psychosocial methods to minimise the impact of cancer on a person)
  • evaluate progress by measuring patterns and trends.

There are three basic ways to promote research: support for the people who do the research; support for the specific projects they design to test a hypothesis to answer a defined question; and support for the infrastructure needed to do the research. The Cancer Council invests in all three types of support, although the balance between them may vary from time to time depending changes in the science or in the operating environment. Examples include:

  • Several years ago it became clear to our Medical and Scientific Committee that ‘banks’ of biological material from cancer patients (e.g. tumour samples) would be essential for researchers to draw upon as they investigated processes using new knowledge and techniques of molecular biology. The Cancer Council therefore funded a project to develop a scheme for collecting tissue at a number of centres for access by researchers. This initiative later led to a $7.1 million grant from the State Government to set up the Victorian Cancer Biobank.
  • In 2005, we identified a gap in the cancer research workforce: for positions available for suitably qualified medical scientists who were also cancer clinicians to pursue research. Usually their clinical workload allowed too little time for research. As a result, in 2006 we awarded two prestigious and well-funded clinical fellowships – the Dunlop Fellowship and the Colebatch Fellowship – which allow the recipients to spend most of their time on research while retaining sufficient clinical work to maintain touch.
  • In 2006, we launched a scheme unique in Australia called the Venture Grants scheme, which gives scientists a chance to take some risks in pursuit of an original idea that could yield a big gain in knowledge. This scheme was a response to the trend among the major funding schemes to favour ‘safer’ projects where the likelihood of some knowledge gain was relatively high but the extent of the advance in knowledge likely to be relatively small.

How is cancer research coordinated worldwide?

There is no single body which coordinates cancer research worldwide, nor would such a system achieve anything even if it were possible.

The main objective is to build world cancer knowledge from research as rapidly as possible. Cancer researchers exist  in a worldwide community of researchers, and ‘market forces’ work quite well to minimise duplication of effort and promote stepwise accumulation of knowledge. Within countries, as an incentive for coordination, funding agencies often give preference to collaborative applications that include researchers from multiple sites and different disciplines. National and international registers of clinical trials enhance coordination, as well as ensuring that patients have the best chance of finding a trial they might be eligible to enter.  

Some duplication of results is always desirable in science in order to have a high level of confidence in the evidence on which to base actions. The healthy competitiveness of researchers also militates in favour of them keeping up to date with other scientists’ work in order to identify the ‘next’ opportunity to investigate an original idea. Online access to all the latest scientific journals and scientific conferences assist in this process.

Where does the money come fromWhere does the money come from?

Around half of our research income comes from charitable donations and fundraising. The rest comes from government grants.

This figure shows our income sources for 2006.

Where is the money used?

  • Donors’ money is used to fund researchers in institutions such as:
  • Austin Health
  • Austin Research Institute
  • Baker Heart Research Institute
  • Deakin University
  • Howard Florey Institute
  • Ludwig Institute for Cancer Research
  • Monash University
  • Murdoch Children’s Research Institute
  • Peter MacCallum Cancer Centre
  • Royal Melbourne Hospital
  • Royal Women’s Hospital
  • St Vincent’s Hospital
  • St Vincent’s Institute
  • University of Melbourne
  • Victorian Breast Cancer Research Consortium
  • Walter & Eliza Hall Institute of Medical Research


We also support cancer clinical trials at these hospitals, including patients from all over Victoria:

  • The Alfred
  • Austin Health
  • Ballarat Health Services
  • Ballarat Private Oncology Services
  • Bendigo Health
  • Border Medical Oncology Wodonga
  • Box Hill Hospital
  • Barwon Health
  • Maroondah Hospital Breast Unit
  • Mercy Hospital For Women
  • Mercy Private Breast Clinic
  • Monash Medical Centre
  • Peninsula Health
  • Peter MacCallum Cancer Centre
  • Royal Children’s Hospital
  • Royal Melbourne Hospital
  • Royal Women’s Hospital
  • St Vincent’s Hospital
  • Western Hospital

Who selects and monitors Cancer Council research?

Accountability

Process: Peer review 

Research funding for our biomedical researchers is allocated by our Executive Committee, on advice from our Medical and Scientific Committee.

Applications for research funding are called for and assessed and ranked by expert committees. This is called ‘peer review’. This expert peer review process gives priority to promising research and is a way of ensuring that we do not duplicate research done elsewhere.

Then the Medical and Scientific Committee decides which applications should be funded, for how much and for how long.

This is a highly competitive process. Only about two in five applications are successful. Unfortunately we often cannot fund projects that we identify as worthwhile, due to lack of money.

Criteria

We fund the best quality research based on the research proposal and the track record (ability, expertise and publication record) of the research team.

We do not give priority to any particular type of cancer.

Accountability

Researchers are required to report annually on the progress of their research.

Four hundred prominent Victorian cancer specialists are active in our committees, including the Medical and Scientific Committee and the Victorian Cooperative Oncology Group.

How do scientists talk to each other about cancer research?

Science and medicine are highly competitive but it’s in a researcher’s interest to publish.

Scientists communicate their research at conferences and through letters and articles in medical and scientific journals. Increasingly, electronic journal publication is improving speedy access to new findings.

Research and results are scrutinised by peers for errors and oversights, and scientific consensus about what evidence ‘holds up’ is usually reached quite quickly.

How do you know when research is real science?

For research to be valid, it needs to be conducted by accepted scientific standards. When testing treatments, for example, this means conducting randomised controlled trials where possible, to eliminate the problem of bias.

‘Real science’ is published after a process of peer review by a reputable medical or science journal. When looking at research findings, check that the findings have been published in a genuine peer-reviewed medical or scientific journal. A good place to start is PubMed, a service of the US National Library of Medicine, which includes over 16 million citations from MEDLINE and other life science journals for biomedical articles from 1950: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed

What is ‘evidence-based’?

Evidence-based medicine is treatment based on current  knowledge, obtained through scientific approaches. Essentially, this means that the measures used in the research are reliable and valid and that extraneous factors that might lead to false conclusions can be excluded because the design of the research was sound.

Clinical trials are an important part of the development of evidence.

Clinical practice guidelines are prepared to let doctors know what this evidence says about the current best way to treat patients with a particular illness.

How is research organised and funded in Australia?

Research projects in this country, and overseas, generally fall into 5 categories:

  • research developed and funded ‘commercially’ by a business like a pharmaceutical (drug) company
  • research developed by a group of doctors who share research interests and have joined together to form a ‘cooperative group’
  • research developed by one or more researchers that is funded by a grant from a government agency or a non-profit organisation. The National Health and Medical Research Council is the biggest government funder of medical research and The Cancer Council Victoria is the largest non-government funder of cancer research in Victoria 
  • research developed by one or more researchers that is not funded by anyone external, but is supported by the researcher’s hospital or university
  • research developed and conducted by a student researcher under the supervision of another experienced researcher.

Some research projects are a combination of two or three of these categories.

 

What's a conflict of interest in cancer research? 

When a person has more than one role, like ‘clinician,’ ‘researcher’ and ‘expert advisor,’ there is a possibility that his or her interests can come into conflict with one another.

Conflicts of interest can also arise when a researcher has a financial interest in a company that is providing funding or other support for his or her research project.

A person having more than one interest does not necessarily mean that the person has a conflict of interest. It may be perfectly ethical, even preferable, for a researcher to have many interests at the same time.

However, it is also important that the person tells someone that he or she has these interests. This is called a ‘declaration of interests’ and is required by the hospitals, universities and other professional organisations where research is conducted in Australia. In some situations, these institutions and organisations may also require that a researcher withdraw from a research project because of the nature of the interests that are in conflict with one another.

The hospitals, universities and other professional organisations where research is conducted in Australia have conflict of interest policies to govern their employees or members. If you are interested in learning more about these policies, you can contact the institution or organisation and ask to see the policy.

Download a copy of our brochure Cancer research and conflict of interest

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