Occupational exposures

Tuesday 30 September, 2008

Cancer sites for which relationships with occupational exposures are well established in human studies

Site

Agent or Industrial Process

Bladder

Benzidine, 2-naphthylamine; 4-Aminobiphenyl (xenylamine)
Coal tar pitch volatiles (aluminum reduction plants, chimney sweeps)
Maufacture of cetain dyes (e.g. auramine and magenta)
Gas retorts
Rubber and cable-making industries 

Blood (leukaemia)

Benzene
X-radiation

Bone

Radium, mesothorium

Larynx

Mustard gas
Sulfuric acid mist

Liver (angiosarcoma)

Arsenic (inorganic compounds)
Vinyl chloride

Lung, bronchus

Arsenic (inorganic compounds)
Asbestos
Beryllium and beryllium compounds
Bis(chloromethyl) ether, chloromethyl methyl ether
Cadmium and cadmium compounds
Chromim compounds
Coal carbonisation process (coke ovens, gas retorts,
producer gas)
Coal tar pitch volatiles (roofing materials, aluminium
reduction plants, chimney sweeps)
Foundry workers
Iron ore (hematite ) mining
Mustard gas
Nickel and nickel compounds
Painters
Radiation (radioactive ores or radon)
Sulfuric acid mist

Nasal cavity, sinuses

Isopropanol manufacture by strong acid process
Mustard gas
Nickel and nickel compounds
Radium, mesothorium
Shoe manufacturing (leather dust?)
Woodworking (wood dust?)

Peritoneum (mesothelioma)

Asbestos

Pharynx

Mustard gas

Pleura (mesothelioma)

Asbestos

Skin (including scrotum)

Arsenic (inorganic compounds)
Coal hydrogenation
Coal tar products (mainly coal tar, creosote pitch, soot)
Mineral oils (from coal, petroleum, shale)
Ultraviolet light
X-radiation

 

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