Leukaemia suppressor genes of mouse and man

Lead researcher

Dr Wendy Cook & Dr Melissa Southey

Years funded

In order to treat cancer we need to know the genes responsible for its prevention, and how they act. By studying leukaemia (cancer of blood cells) in mice, we have proved the preventive role of one gene. Comparing mouse and human leukaemias has allowed us to predict the chromosomal location of other genes with this ability. Now we are poised to identify these genes, and to reveal how they work together against cancer. This will be a further step towards the design of new therapies to control leukaemia.