A new cause of breast cancer predisposition.

Lead researcher

Dr Alexander Dobrovic To be confirmed

Peter MacCallum Cancer Centre

Years funded

Research into the early detection of breast cancer in adults. A small proportion of breast cancer is caused by mutations in the breast cancer predisposition genes, BRCA1 or BRCA2 but the majority of breast cancers have no identifiable genetic predisposition. In this study, we propose that BRCA1 can be inactivated in all cells of the body by a novel mechanism which can predispose to breast cancer. This will allow a possible new method for screening for risk of breast cancer by using a blood test.

Award / Duration

Research Grant: 2007