Elucidating mechanisms of resistance to therapeutic inhibition of RNA polymerase 1 transcription

Lead researcher

Dr Gretchen Poortinga, Prof Grant McArthur, Prof Ross Hannan

Peter MacCallum Cancer Centre, Division of Research

Years funded

We have developed the first inhibitor, showing potential for potency in human blood malignancies, of a key step in the process of cell growth that is critical to cancer cell survival. This project aims to advance these studies by understanding how cancer can relapse under this therapy and thus provide better outcomes for patients.

Funding Body

Cancer Council Research Grant


$99,483 pa 2016 and 2017, $99,023 in 2018