Lead researcher
Dr James Murphy, Dr Silvia Alvarez-Diaz, A/Prof Matthias Ernst
Institution
Cell Signalling and Cell Death, The Walter and Eliza Hall Institute of Medical Research
Years funded
2015-2017
Colorectal cancer (CRC) is the second most
common type of cancer in Australia. Unfortunately, only a small number of CRCs
are detected in the early stages, and once CRC has spread to other parts of the
body, current therapies are ineffective. We will use clinically relevant mouse
models to define the contribution of necroptosis, a new programmed cell death
pathway, to the initiation and progression of CRC. Our objective is to improve
the development of new anti-cancer therapies for advanced CRC.
Funding Body
Cancer Council Research Grant
Funding
$99,826 per annum