BMP7 regulation of telomerase

Lead researcher

A/Prof Jun-Ping Liu

Institution
Monash University

Years funded
2008

This project determines the role of growth factor BMP7 in regulating the size of chromosome end (telomere) and thereby cell lifespan. Preliminary data showed that BMP7 inhibits breast cancer cells by causing telomere shortening. Further studies will establish specificities and mechanisms of action of BMP7 through BMP7 receptors in breast cancer cells.

Funding

95000