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The association of alcohol & HRT with breast cancer risk in the MCCS

Investigators

Gertig, D., Erbas, B., Hopper, J., Giles, G., English, D.

Objectives

  • To evaluate the association between Hormone Replacement Therapy (HRT) use and incidence of breast cancer in the Melbourne Collaborative Cohort Study (MCCS), adjusting for other breast cancer risk factors. The association of HRT by tumour size, grade and ER/PR status will also be examined where numbers permit.
  • To evaluate the association between alcohol use and breast cancer incidence in the MCCS cohort, adjusting for other breast cancer risk factors.

Publications

Gertig DM, Fletcher AS, English DR, Macinnis RJ, Hopper JL, Giles GG. Hormone therapy and breast cancer: What factors modify the association? Menopause. 2006;13:178-184

Simpson JA, English DR, Macinnis RJ, Gertig DM, Hopper JL, Giles GG. A comparison of different methods for including 'age at menopause' in analyses of the association between hormone replacement therapy use and breast cancer. J Fam Plann Reprod Health Care. 2007;33:11-16