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CED Publications 2016

Breast Cancer

Abubakar M, Orr N, Daley F, et al. Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups. Breast Cancer Res. 2016;18:104

Bassett JK, Hodge AM, English DR, MacInnis RJ, Giles GG. Plasma phospholipids fatty acids, dietary fatty acids, and breast cancer risk. Cancer Causes Control. 2016;27(6):759-73

Catucci I, Radice P, Milne RL, Couch FJ, Southey MC, Peterlongo P. The PALB2 p.Leu939Trp mutation is not associated with breast cancer risk. Breast Cancer Res. 2016;18:111 

Dartois L, Fagherazzi G, Baglietto L, Boutron-Ruault MC, Delaloge S, Mesrine S, Clavel-Chapelon F. Proportion of premenopausal and postmenopausal breast cancers attributable to known risk factors: Estimates from the E3N-EPIC cohort. Int J Cancer. 2016;138(10):2415-27

de la Hoya M, Soukarieh O, Lopez-Perolio I, et al. Combined genetic and splicing analysis of BRCA1 c.[594-2A>C; 641A>G] highlights the relevance of naturally occurring in-frame transcripts for developing disease gene variant classification algorithms. Hum Mol Genet. 2016;25:2256-2268 

Dite GS, MacInnis RJ, Bickerstaffe A, Dowty JG, Allman R, Apicella C, Milne RL, Tsimiklis H, Phillips KA, Giles GG, Terry MB, Southey MC, Hopper JL. Breast cancer risk prediction using clinical models and 77 independent risk-associated SNPs for women aged under 50 years: Australian Breast Cancer Family Registry. Cancer Epidemiol Biomarkers Prev. 2016;25(2):359-65

Dunning AM, Michailidou K, Kuchenbaecker KB, et al. Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170. Nat Genet. 2016;48(4):374-86

Easton DF, Lesueur F, Decker B, et al. No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing. J Med Genet. 2016;53(5):298-309

Emaus MJ, Peeters PH, Bakker MF, et al. Vegetable and fruit consumption and the risk of hormone receptor-defined breast cancer in the EPIC cohort. Am J Clin Nutr. 2016;103(1):168-77 

Gaudet MM, Barrdahl M, Lindstrom S, Travis RC, Auer PL, Buring JE, Chanock SJ, Heather Eliassen A, Gapstur SM, Giles GG, Gunter M, Haiman C, Hunter DJ, Joshi AD, Kaaks R, Khaw KT, Lee IM, Le Marchand L, Milne RL, Peeters PH, Sund M, Tamimi R, Trichopoulou A, Weiderpass E, Yang XR, Prentice RL, Feigelson HS, Canzian F, Kraft P. Interactions between breast cancer susceptibility loci and menopausal hormone therapy in relationship to breast cancer in the Breast and Prostate Cancer Cohort Consortium. Breast Cancer Res Treat. 2016;155(3):531-40

Ghoussaini M, French JD, Michailidou K, et al. Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation. Am J Hum Genet. 2016;99(4):903-11

Hamdi Y, Soucy P, Adoue V, et al. Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21. Oncotarget. 2016;7(49):80140-63 

Hopper JL, Nguyen TL, Stone J, Aujard K, Matheson MC, Abramson MJ, Burgess JA, Walters EH, Dite GS, Bui M, Evans C, Makalic E, Schmidt DF, Ward G, Jenkins MA, Giles GG, Dharmage SC, Apicella C. Childhood body mass index and adult mammographic density measures that predict breast cancer risk. Breast Cancer Res Treat. 2016;156(1):163-70

Jayasekara H, MacInnis RJ, Hodge AM, Room R, Milne RL, Hopper JL, Giles GG, English DR. Is breast cancer risk associated with alcohol intake before first full-term pregnancy? Cancer Causes Control. 2016;27(9):1167-74

Jung S, Wang M, Anderson K, et al. Alcohol consumption and breast cancer risk by estrogen receptor status: in a pooled analysis of 20 studies. Int J Epidemiol. 2016;45(3):916-28 

Krishnan K, Baglietto L, Apicella C, Stone J, Southey MC, English DR, Giles GG, Hopper JL. Mammographic density and risk of breast cancer by mode of detection and tumor size: a case-control study. Breast Cancer Res. 2016;18:63

Lei J, Rudolph A, Moysich KB, et al. Genetic variation in the immunosuppression pathway genes and breast cancer susceptibility: a pooled analysis of 42,510 cases and 40,577 controls from the Breast Cancer Association Consortium. Hum Genet. 2016;135(1):137-54

Liu J, Loncar I, Collee JM, et al. rs2735383, located at a microRNA binding site in the 3'UTR of NBS1, is not associated with breast cancer risk. Scientific reports. 2016;6:36874

Maas P, Barrdahl M, Joshi AD, et al. Breast Cancer Risk From Modifiable and Nonmodifiable Risk Factors Among White Women in the United States. JAMA Oncology. 2016;2(10):1295-302

MacInnis RJ, Pike MC, Hopper JL. Risk-Reducing Surgery in Hereditary Breast and Ovarian Cancer. N Engl J Med. 2016;374:2403-2404

Milne RL, Antoniou A. Modifiers of breast and ovarian cancer risks for BRCA1 and BRCA2 mutation carriers. Endocrine-related cancer. 2016;23(10):T69-84

Pelttari LM, Khan S, Vuorela M, et al. RAD51B in Familial Breast Cancer. PLoS One. 2016;11:e0153788

Petridis C, Brook MN, Shah V, et al. Genetic predisposition to ductal carcinoma in situ of the breast. Breast Cancer Res. 2016;18:22

Phillips KA, Collins IM, Milne RL, McLachlan SA, Friedlander M, Hickey M, Stern C, Hopper JL, Fisher R, Kannemeyer G, Picken S, Smith CD, Kelsey TW, Anderson RA, Kathleen Cuningham Consortium for Research into Familial Breast C. Anti-Mullerian hormone serum concentrations of women with germline BRCA1 or BRCA2 mutations. Human reproduction. 2016;31(5):1126-32

Purrington KS, Visscher DW, Wang C, Yannoukakos D, Hamann U, Nevanlinna H, Cox A, Giles GG, Eckel-Passow JE, Lakis S, Kotoula V, Fountzilas G, Kabisch M, Rudiger T, Heikkila P, Blomqvist C, Cross SS, Southey MC, Olson JE, Gilbert J, Deming-Halverson S, Kosma VM, Clarke C, Scott R, Jones JL, Zheng W, Mannermaa A, Jane Carpenter for AI, Eccles DM, Vachon CM, Couch FJ. Genes associated with histopathologic features of triple negative breast tumors predict molecular subtypes. Breast Cancer Res Treat. 2016;157(1):117-31

Schmidt MK, Hogervorst F, van Hien R, et al. Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers. J Clin Oncol. 2016;34(23):2750-60

Scott CM, Joo JE, O'Callaghan N, Buchanan DD, Clendenning M, Giles GG, Hopper JL, Wong EM, Southey MC. Methylation of Breast Cancer Predisposition Genes in Early-Onset Breast Cancer: Australian Breast Cancer Family Registry. PLoS One. 2016;11:e0165436 

Shi J, Zhang Y, Zheng W, et al. Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer. Int J Cancer. 2016;139(6):1303-17

Simapivapan P, Boltong A, Hodge A. To what extent is alcohol consumption associated with breast cancer recurrence and second primary breast cancer?: A systematic review. Cancer treatment reviews. 2016;50:155-167

Sung H, Garcia-Closas M, Chang-Claude J, et al. Heterogeneity of luminal breast cancer characterised by immunohistochemical expression of basal markers. Br J Cancer. ;114(3):298-304

Wong EM, Joo JE, McLean CA, Baglietto L, English DR, Severi G, Wu HC, Terry MB, Hopper JL, Milne RL, Giles GG, Southey MC. Analysis of the breast cancer methylome using formalin-fixed paraffin-embedded tumour. Breast Cancer Res Treat. 2016;160(1):173-80

Wyszynski A, Hong CC, Lam K, et al. An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression. Hum Mol Genet. 2016;25(17):3863-76 

Zeng C, Guo X, Long J, et al. Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus. Breast Cancer Res. 2016;18(1):64

Zhao Z, Wen W, Michailidou K, et al. Association of genetic susceptibility variants for type 2 diabetes with breast cancer risk in women of European ancestry. Cancer Causes Control. 2016;27(5):679-93


Colorectal Cancer 

Chau R, Jenkins MA, Buchanan DD, Ait Ouakrim D, Giles GG, Casey G, Gallinger S, Haile RW, Le Marchand L, Newcomb PA, Lindor NM, Hopper JL, Win AK. Determining the familial risk distribution of colorectal cancer: a data mining approach. Fam Cancer. 2016;15(2):241-51 

Chau R, Dashti SG, Ait Ouakrim D, Buchanan DD, Clendenning M, Rosty C, Winship IM, Young JP, Giles GG, Macrae FA, Boussioutas A, Parry S, Figueiredo JC, Levine AJ, Ahnen DJ, Casey G, Haile RW, Gallinger S, Le Marchand L, Thibodeau SN, Lindor NM, Newcomb PA, Potter JD, Baron JA, Hopper JL, Jenkins MA, Win AK. Multivitamin, calcium and folic acid supplements and the risk of colorectal cancer in Lynch syndrome. Int J Epidemiol. 2016;45(3):940-53

Jayasekara H, Reece JC, Buchanan DD, Rosty C, Dashti SG, Ouakrim DA, Winship IM, Macrae FA, Boussioutas A, Giles GG, Ahnen DJ, Lowery J, Casey G, Haile RW, Gallinger S, Le Marchand L, Newcomb PA, Lindor NM, Hopper JL, Parry S, Jenkins MA, Win AK. Risk factors for metachronous colorectal cancer following a primary colorectal cancer: A prospective cohort study. Int J Cancer. 2016;139(5):1081-90

Jayasekara H, Reece JC, Buchanan DD, Ahnen DJ, Parry S, Jenkins MA, Win AK. Risk factors for metachronous colorectal cancer or polyp: A systematic review and meta-analysis. J Gastroenterol Hepatol. 2016;139(5):1081-90

Jayasekara H, MacInnis RJ, Williamson EJ, Hodge AM, Clendenning M, Rosty C, Walters R, Room R, Southey MC, Jenkins MA, Milne RL, Hopper JL, Giles GG, Buchanan DD and English DR. Lifetime alcohol intake is associated with an increased risk of KRAS+ and BRAF-/KRAS- but not BRAF+ colorectal cancer. Int J Cancer. 2016;139(5):1081-90.

Jenkins MA, Makalic E, Dowty JG, Schmidt DF, Dite GS, MacInnis RJ, Ait Ouakrim D, Clendenning M, Flander LB, Stanesby OK, Hopper JL, Win AK, Buchanan DD. Quantifying the utility of single nucleotide polymorphisms to guide colorectal cancer screening. Future oncology. 2016;12:503-513

Lynch BM, Boyle T, Winkler E, Occleston J, Courneya KS, Vallance JK. Patterns and correlates of accelerometer-assessed physical activity and sedentary time among colon cancer survivors. Cancer Causes Control. 2016;27(1):59-68

Lynch BM, Mihala G, Beesley VL, Wiseman AJ, Gordon LG. Associations of health behaviours with return to work outcomes after colorectal cancer. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 2016;24(2):865-70  

Karahalios A, Simpson JA, Baglietto L, MacInnis RJ, Hodge AM, Giles GG, English DR. Change in weight and waist circumference and risk of colorectal cancer: results from the Melbourne Collaborative Cohort Study. BMC Cancer. 2016;16:1-7 

Shang J, Reece JC, Buchanan DD, Giles GG, Figueiredo JC, Casey G, Gallinger S, Thibodeau SN, Lindor NM, Newcomb PA, Potter JD, Baron JA, Hopper JL, Jenkins MA, Win AK. Cholecystectomy and the risk of colorectal cancer by tumor mismatch repair deficiency status. International journal of colorectal disease. 2016;31(8):1451-7

van Roekel EH, Winkler EA, Bours MJ, Lynch BM, Willems PJ, Meijer K, Kant I, Beets GL, Sanduleanu S, Healy GN, Weijenberg MP. Associations of sedentary time and patterns of sedentary time accumulation with health-related quality of life in colorectal cancer survivors. Preventive medicine reports. 2016;4:262-269.

Prostate Cancer  

Bonilla C, Lewis SJ, Martin RM, et al. Pubertal development and prostate cancer risk: Mendelian randomization study in a population-based cohort. BMC Medicine. 2016;14:66

Bonilla C, Lewis SJ, Rowlands MA, et al. Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: Genetic variants as instruments for circulating levels. Int J Cancer. 2016;139(7):1520-33

Bull CJ, Bonilla C, Holly JM, Perks CM, Davies N, Haycock P, Yu OH, Richards JB, Eeles R, Easton D, Kote-Jarai Z, Amin Al Olama A, Benlloch S, Muir K, Giles GG, MacInnis RJ, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Neal D, Pashayan N, Khaw KT, Stanford JL, Blot WJ, Thibodeau S, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Park J, Kaneva R, Batra J, Teixeira MR, Micheal A, Pandha H, Smith GD, Lewis SJ, Martin RM, Practical Consortium. Blood lipids and prostate cancer: a Mendelian randomization analysis. Cancer Medicine. 2016;5(6):1125-36

Darabi H, Beesley J, Droit A, et al. Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs). Scientific reports. 2016;6:32512

Duchesne GM, Woo HH, Bassett JK, Bowe SJ, D'Este C, Frydenberg M, King M, Ledwich L, Loblaw A, Malone S, Millar J, Milne R, Smith RG, Spry N, Stockler M, Syme RA, Tai KH, Turner S. Timing of androgen-deprivation therapy in patients with prostate cancer with a rising PSA (TROG 03.06 and VCOG PR 01-03 [TOAD]): a randomised, multicentre, non-blinded, phase 3 trial. Lancet Oncol. 2016;17(6):727-37

Gusev A, Shi H, Kichaev G, Pomerantz M, et al. Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation. Nature Communications. 2016;7:10979

Khankari NK, Murff HJ, Zeng C, Wen W, Eeles RA, Easton DF, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Donovan JL, Pashayan N, Khaw KT, Stanford JL, Blot WJ, Thibodeau SN, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Park J, Kaneva R, Batra J, Teixeira MR, Pandha H, Zheng W, consortium P. Polyunsaturated fatty acids and prostate cancer risk: a Mendelian randomisation analysis from the PRACTICAL consortium. Br J Cancer. 2016;115(5):624-31

MacInnis RJ, Schmidt DF, Makalic E, Severi G, FitzGerald L, Reumann M, Kapuscinski MK, Kowalczyk A, Zhou Z, Goudey BW, Qian G, Bui M, Park DJ, Freeman A, Southey MC, Amin Al Olama A, Kote-Jarai Z, Eeles RA, Hopper JL, Giles GG. Use of a novel non-parametric version of DEPTH to identify genomic regions associated with prostate cancer risk. Cancer Epidemiol Biomarkers Prev. 2016;25(12):1619-24.

O'Kane D, Papa N, Lawrentschuk N, Syme R, Giles G, Bolton D. Supervisor volume affects oncological outcomes of trainees performing open radical prostatectomy. ANZ J Surg. 2016;86(4):249-54 

Saunders EJ, Dadaev T, Leongamornlert DA, Olama AA, Benlloch S, Giles GG, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Neal D, Pasayan N, Khaw KT, Stanford JL, Blot WJ, Thibodeau SN, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Park JY, Kaneva R, Batra J, Teixeira MR, Pandha H, Govindasami K, Muir K, Collaborators UKGPCS, Collaborators UKPS, Consortium P, Easton DF, Eeles RA, Kote-Jarai Z. Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array. Br J Cancer. 2016;114(8):945-52

Travis RC, Appleby PN, Martin RM, et al. A meta-analysis of individual participant data reveals an association between circulating levels of IGF-I and prostate cancer risk. Cancer Res. 2016;76(8):2288-300

Wu K, Spiegelman D, Hou T, Albanes D, et al. Associations between unprocessed red and processed meat, poultry, seafood and egg intake and the risk of prostate cancer: A pooled analysis of 15 prospective cohort studies. Int J Cancer. 2016;138(10):2368-82 

More Than One Cancer Type 

Kar SP, Beesley J, Amin Al Olama A, et al. Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types. Cancer Discovery. 2016;6(9):1052-67.

Lawrenson K, Kar S, McCue K, et al. Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus. Nature communications. 2016;7:12675. 

Ovarian Cancer Association Consortium, Breast Cancer Association Consortium, Consortium of Investigators of Modifiers of BRCA1/2, et al. No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer. Gynecol Oncol. 2016;141(2):386-401

Southey MC, Goldgar DE, Winqvist R, ... Milne RL. PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS. J Med Genet. 2016;53(12):800-11.  

Other Cancers  

Anantharaman D, Muller DC, Lagiou P, et al. Combined effects of smoking and HPV16 in oropharyngeal cancer. Int J Epidemiol. 2016;45(3):752-61 

Berndt SI, Camp NJ, Skibola CF, et al. Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia. Nature Communications. 2016;7:10933

Cheng TH, Thompson DJ, O'Mara, TA, et al. Five endometrial cancer risk loci identified through genome-wide association analysis. Nat Genet. 2016;48(6):667-74

Cuellar-Partida G, Lu Y, Dixon SC, et al. Assessing the genetic architecture of epithelial ovarian cancer histological subtypes. Hum Genet. 2016;135(7):741-56

Dixon SC, Nagle CM, Thrift AP, et al. Adult body mass index and risk of ovarian cancer by subtype: a Mendelian randomization study. Int J Epidemiol. 2016;45(3)884-95.

Dugué PA, Hodge AM, Brinkman MT, Bassett JK, Shivappa N, Hebert JR, Hopper JL, English DR, Milne RL, Giles GG. Association between selected dietary scores and the risk of urothelial cell carcinoma: A prospective cohort study. Int J Cancer. 2016;139(6):1251-60

Dugué PA, Brinkman MT, Milne RL, Wong EM, FitzGerald LM, Bassett JK, Joo JE, Jung CH, Makalic E, Schmidt DF, Park DJ, Chung J, Ta AD, Bolton DM, Lonie A, Longano A, Hopper JL, Severi G, Saffery R, English DR, Southey MC, Giles GG. Genome-wide measures of DNA methylation in peripheral blood and the risk of urothelial cell carcinoma: a prospective nested case-control study. Br J Cancer. 2016;115(6):664-73 

Goossens ME, Isa F, Brinkman M, et al. International pooled study on diet and bladder cancer: the bladder cancer, epidemiology and nutritional determinants (BLEND) study: design and baseline characteristics. Archives of public health = Archives belges de sante publique. 2016;74:30

Hampras SS, Sucheston-Campbell LE, Cannioto R, et al. Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer. Oncotarget. 2016;7(43):69097-110.

Hodge AM, Bassett JK, Shivappa N, Hebert JR, English DR, Giles GG, Severi G. Dietary inflammatory index, Mediterranean diet score, and lung cancer: a prospective study. Cancer Causes Control. 2016;27(7):907-17

Hofmann JN, Birmann BM, Teras LR, Pfeiffer RM, Wang Y, Albanes D, Baris D, Colditz GA, De Roos AJ, Giles GG, Hosgood HD, Lan Q, Landgren O, Liao LM, Rothman N, Weinstein SJ, Pollak MN, Neuhouser ML, Purdue MP. Low levels of circulating adiponectin are associated with multiple myeloma risk in overweight and obese individuals. Cancer Res. 2016;76(7):1935-41

Lee AW, Templeman C, Stram DA, Beesley J, Tyrer J, Berchuck A, Pharoah PP, Chenevix-Trench G, Pearce CL. Evidence of a genetic link between endometriosis and ovarian cancer. Fertility and sterility. 2016;105(1):35-43 e1-10

Kachuri L, Amos CI, McKay JD, et al. Fine-mapping of chromosome 5p15.33 based on a targeted deep sequencing and high density genotyping identifies novel lung cancer susceptibility loci. Carcinogenesis. 2016;37(1):96-105 

Machiela MJ, Lan Q, Slager SL, et al. Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes. Hum Mol Genet. 2016;25:1663-1676

Neale RE, Armstrong BK, Baxter C, Romero BD, Ebeling P, English DR, Kimlin MG, McLeod DS, RL OC, van der Pols JC, Venn AJ, Webb PM, Whiteman DC, Wockner L. The D-Health Trial: A randomized trial of vitamin D for prevention of mortality and cancer. Contemporary Clinical Trials. 2016;48:83-90

Oberoi DV, White V, Jefford M, Giles GG, Bolton D, Davis I, Winship I, Prince HM, Millar J, Harrison S, Kay A, Hill D. Caregivers' information needs and their 'experiences of care' during treatment are associated with elevated anxiety and depression: a cross-sectional study of the caregivers of renal cancer survivors. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 2016;24(10):4177-86

Obon-Santacana M, Lujan-Barroso L, Travis RC, et al. Acrylamide and glycidamide hemoglobin adducts and epithelial ovarian cancer: a nested case-control study in non-smoking postmenopausal women from the EPIC cohort. Cancer Epidemiol Biomarkers Prev. 2016;25(1):127-34.

Ong JS, Cuellar-Partida G, Lu Y, et al. Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study. Int J Epidemiol. 2016;45(5):1619-30.

Painter JN, O'Mara TA, Marquart L, et al. Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer. Cancer Epidemiol Biomarkers Prev. 2016;25:1503-1510

Permuth JB, Reid B, Earp M, et al. Inherited variants affecting RNA editing may contribute to ovarian cancer susceptibility: results from a large-scale collaboration. Oncotarget. 2016;7:72381-72394 

Rand KA, Song C, Dean E, et al. A meta-analysis of multiple myeloma risk regions in African and European ancestry populations identifies putatively functional loci. Cancer Epidemiol Biomarkers Prev. 2016;25(12):1609-1618.  

Terry KL, Schock H, Fortner RT, et al. A prospective evaluation of early detection biomarkers for ovarian cancer in the European EPIC cohort. Clin Cancer Res. 2016;22(18):4664-75.

Thompson DJ, O'Mara TA, Glubb DM, et al. CYP19A1 fine-mapping and Mendelian randomisation: estradiol is causal for endometrial cancer. Endocrine-related cancer. 2016;23(2):77-91 

Vuong K, Armstrong BK, Weiderpass E and the Australian Melanoma Family Study Investigators. Development and External Validation of a Melanoma Risk Prediction Model Based on Self-assessed Risk Factors. JAMA dermatology. 2016;152(8):889-96

Wong Doo N, Makalic E, Joo JE, Vajdic CM, Schmidt DF, Wong EM, Jung CH, Severi G, Park DJ, Chung J, Baglietto L, Prince HM, Seymour JF, Tam C, Hopper JL, English DR, Milne RL, Harrison SJ, Southey MC, Giles GG. Global measures of peripheral blood-derived DNA methylation as a risk factor in the development of mature B-cell neoplasms. Epigenomics. 2016;8(1):55-66 

Zhang M, Wang Z, Obazee O, et al. Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21. Oncotarget. 2016; 7(41):66328-43.

Other Conditions  

Callisaya ML, Blizzard L, Martin K, Srikanth VK. Gait initiation time is associated with the risk of multiple falls-A population-based study. Gait & posture. 2016;49:19-24

Del Gobbo LC, Imamura F, Aslibekyan S et al and Aging Research in Genomic Epidemiology Fatty, Acids Outcomes Research, Consortium. Omega-3 Polyunsaturated Fatty Acid Biomarkers and Coronary Heart Disease: Pooling Project of 19 Cohort Studies. JAMA internal medicine. 2016;176(8):1155-66

Cooper J, Borland R, McKee SA, Yong HH, Dugué PA. Depression motivates quit attempts but predicts relapse: differential findings for gender from the International Tobacco Control Study. Addiction. 2016;111(8):1438-47

Dharmage SC, Perret JL, Burgess JA, Lodge CJ, Johns DP, Thomas PS, Giles GG, Hopper JL, Abramson MJ, Walters EH, Matheson MC. Current asthma contributes as much as smoking to chronic bronchitis in middle age: a prospective population-based study. International journal of chronic obstructive pulmonary disease. 2016;11:1911-1920

Dugué PA, Geurts YM, Milne RL, Lockett GA, Zhang H, Karmaus W, Holloway JW. Is there an association between season of birth and blood DNA methylation in adulthood?  Allergy. 2016;71:1501-1504 

Finger RP, Chong E, McGuinness MB, Robman LD, Aung KZ, Giles G, Baird PN, Guymer RH. Reticular Pseudodrusen and Their Association with Age-Related Macular Degeneration: The Melbourne Collaborative Cohort Study. Ophthalmology. 2016;123(3):599-608 

Hadgraft NT, Healy GN, Owen N, Winkler EA, Lynch BM, Sethi P, Eakin EG, Moodie M, LaMontagne AD, Wiesner G, Willenberg L, Dunstan DW. Office workers' objectively assessed total and prolonged sitting time: Individual-level correlates and worksite variations. Preventive medicine reports. 2016;4:184-191

Harding JL, Sooriyakumaran M, Anstey KJ, Adams R, Balkau B, Brennan-Olsen S, Briffa T, Davis TM, Davis WA, Dobson A, Giles GG, Grant J, Huxley R, Knuiman M, Luszcz M, Mitchell P, Pasco JA, Reid CM, Simmons D, Simons LA, Taylor AW, Tonkin A, Woodward M, Shaw JE, Magliano DJ. Hypertension, antihypertensive treatment and cancer incidence and mortality: a pooled collaborative analysis of 12 Australian and New Zealand cohorts. J Hypertens. 2016;34:149-155 

Heath AK, Williamson EJ, Kvaskoff D, Hodge AM, Ebeling PR, Baglietto L, Neale RE, Giles GG, Eyles DW, English DR. 25-Hydroxyvitamin D concentration and all-cause mortality: the Melbourne Collaborative Cohort Study. Public Health Nutr. 2016:1-10  

Hirakawa Y, Lam TH, Welborn T, Kim HC, Ho S, Fang X, Ueshima H, Suh I, Giles G, Woodward M, Asia Pacific Cohort Studies C. The impact of body mass index on the associations of lipids with the risk of coronary heart disease in the Asia Pacific region. Preventive Medicine Reports. 2016;3:79-82  

Hodge A, Bassett J. What can we learn from dietary pattern analysis? Public Health Nutr. 2016;19:191-194

Hussain SM, Cicuttini FM, Giles GG, Graves SE, Wang Y. Relationship between circulating sex steroid hormone concentrations and incidence of total knee and hip arthroplasty due to osteoarthritis in men. Osteoarthritis Cartilage. 2016;24(8):1408-12

Johnson ST, Lynch B, Vallance J, Davenport MH, Gardiner PA, Butalia S. Sedentary behavior, gestational diabetes mellitus, and type 2 diabetes risk: where do we stand? Endocrine. 2016;52(1):5-10

Kitahara CM, McCullough M, Franceschi S, et al. Anthropometric factors and thyroid cancer risk by histological subtype: pooled analysis of 22 prospective studies. Thyroid : official journal of the American Thyroid Association. 2016;26(2):306-18

Machiela MJ, Zhou W, Karlins E, et al. Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome. Nature communications. 2016;7:11843

Matheson MC, Reece JC, Kandane-Rathnayake RK, Tang ML, Simpson JA, Feather IH, Southey MC, Tsimiklis H, Hopper JL, Morrison SC, Giles GG, Walters EH, Dharmage SC. Mould-sensitised adults have lower Th2 cytokines and a higher prevalence of asthma than those sensitised to other aeroallergens. Allergy. 2016;71(12):1701-11.

McGuinness MB, Karahalios A, Simpson JA, Guymer RH, Robman LD, Hodge AM, Cerin E, Giles GG, Finger RP. Past physical activity and age-related macular degeneration: the Melbourne Collaborative Cohort Study. Br J Ophthalmol. 2016;(100(10):1353-8. 

Perret JL, Walters H, Johns D, Gurrin L, Burgess J, Lowe A, Thompson B, Markos J, Morrison S, Thomas P, McDonald C, Wood-Baker R, Hopper J, Svanes C, Giles G, Abramson M, Matheson M, Dharmage S. Mother's smoking and complex lung function of offspring in middle age: A cohort study from childhood. Respirology. 2016;21(5):911-9

Rodriguez AJ, Scott D, Khan B, Khan N, Hodge A, English DR, Giles GG, Ebeling PR. Low Relative Lean Mass is Associated with Increased Likelihood of Abdominal Aortic Calcification in Community-Dwelling Older Australians. Calcified tissue international. 2016;99(4):340-9.

Shang X, Scott D, Hodge A, Khan B, Khan N, English DR, Giles GG, Ebeling PR, Sanders KM. Adiposity assessed by anthropometric measures has a similar or greater predictive ability than dual-energy X-ray absorptiometry measures for abdominal aortic calcification in community-dwelling older adults. The international journal of cardiovascular imaging. 2016;32(9):1451-60.

Shang X, Scott D, Hodge AM, English DR, Giles GG, Ebeling PR, Sanders KM. Dietary protein intake and risk of type 2 diabetes: results from the Melbourne Collaborative Cohort Study and a meta-analysis of prospective studies. Am J Clin Nutr. 2016;104(5):1352-65.

Shang X, Scott D, Hodge A, Khan B, Khan N, English DR, Giles GG, Ebeling PR, Sanders KM. Adiposity assessed by anthropometric measures has a similar or greater predictive ability than dual-energy X-ray absorptiometry measures for abdominal aortic calcification in community-dwelling older adults. The international journal of cardiovascular imaging. 2016;32:1451-1460

Shang X, Scott D, Hodge AM, English DR, Giles GG, Ebeling PR, Sanders KM. Dietary protein intake and risk of type 2 diabetes: results from the Melbourne Collaborative Cohort Study and a meta-analysis of prospective studies. Am J Clin Nutr. 2016;104:1352-1365 

Tan DJ, Walters EH, Perret JL, Burgess JA, Johns DP, Lowe AJ, Lodge CJ, Hayati Rezvan P, Simpson JA, Morrison S, Thompson BR, Thomas PS, Feather I, Giles GG, Hopper JL, Abramson MJ, Matheson MC, Dharmage SC. Clinical and functional differences between early-onset and late-onset adult asthma: a population-based Tasmanian Longitudinal Health Study. Thorax. 2016v;71(11):981-7. 

Tanamas SK, Ng WL, Backholer K, Hodge A, Zimmet PZ, Peeters A. Quantifying the proportion of deaths due to body mass index- and waist circumference-defined obesity. Obesity (Silver Spring). 2016;24(3):735-4

Vallance JK, Eurich DT, Lynch BM, Gardiner PA, Taylor LM, Jefferis BJ, Johnson ST. Correlates of General and Domain-Specific Sitting Time among Older Adults. American Journal of Health Behavior. 2016;40:362-370

Wang Y, Smith S, Teichtahl AJ, Hodge AM, Wluka AE, Giles GG, Cicuttini FM. Association Between Dietary Intake of Antioxidants and Prevalence of Femoral Head Cartilage Defects and Bone Marrow Lesions in Community-based Adults. J Rheumatol. 2016t;43(10):1885-90.

Scientific methods  

Bassett JK, English DR, Fahey MT, Forbes AB, Gurrin LC, Simpson JA, Brinkman MT, Giles GG, Hodge AM. Validity and calibration of the FFQ used in the Melbourne Collaborative Cohort Study. Public Health Nutr. 2016:1-12

Dugué PA, English DR, MacInnis RJ, Jung CH, Bassett JK, FitzGerald LM, Wong EM, Joo JE, Hopper JL, Southey MC, Giles GG, Milne RL. Reliability of DNA methylation measures from dried blood spots and mononuclear cells using the HumanMethylation450k BeadArray. Scientific reports. 2016;6:30317

Ioannidis NM, Rothstein JH, Pejaver V, et al. REVEL: an Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants. Am J Hum Genet. 2016;99(4):877-85.

Kvaskoff D, Heath AK, Simila HA, Ko P, English DR, Eyles DW. Minimizing Matrix Effects for the Accurate Quantification of 25-Hydroxyvitamin D Metabolites in Dried Blood Spots by LC-MS/MS. Clinical Chemistry. 2016;62(4):639-46

Larson NB, McDonnell S, Albright LC, Teerlink C, Stanford J, Ostrander EA, Isaacs WB, Xu J, Cooney KA, Lange E, Schleutker J, Carpten JD, Powell I, Bailey-Wilson J, Cussenot O, Cancel-Tassin G, Giles G, MacInnis R, Maier C, Whittemore AS, Hsieh CL, Wiklund F, Catolona WJ, Foulkes W, Mandal D, Eeles R, Kote-Jarai Z, Ackerman MJ, Olson TM, Klein CJ, Thibodeau SN, Schaid DJ. Post hoc Analysis for Detecting Individual Rare Variant Risk Associations Using Probit Regression Bayesian Variable Selection Methods in Case-Control Sequencing Studies. Genet Epidemiol. 2016;40(6):461-9

Mishra GD, Chung HF, Pandeya N, Dobson AJ, Jones L, Avis NE, Crawford SL, Gold EB, Brown D, Sievert LL, Brunner E, Cade JE, Burley VJ, Greenwood DC, Giles GG, Bruinsma F, Goodman A, Hayashi K, Lee JS, Mizunuma H, Kuh D, Cooper R, Hardy R, Obermeyer CM, Lee KA, Simonsen MK, Yoshizawa T, Woods NF, Mitchell ES, Hamer M, Demakakos P, Sandin S, Adami HO, Weiderpass E, Anderson D. The InterLACE study: Design, data harmonization and characteristics across 20 studies on women's health. Maturitas. 2016;92:176-185 

O'Kane, D, Papa NP, Manning T, Quinn J, Hawes A, Smith N, McClintock S, Lawrentschuk N, Bolton DM. Contemporary accuracy of digital abdominal X-ray for follow-up of pure calcium urolithiasis; is there still a role? Journal of Endourology / Endourological Society. 2016;30(8):844-9.