What is breast cancer?
Breast cancer is the abnormal growth of the cells lining the breast
ducts or lobules. These abnormal cells have the potential to spread to
other parts of the body. Most breast cancers are invasive. This means
the cancer has spread from the breast ducts or lobules into the
surrounding breast tissue. Invasive breast cancer can be early, locally
advanced or advanced (metastatic). Breast cancer is the most common
cancer among Victorian females.
You can access further information about breast cancer, including
risk factors, symptoms, diagnosis and treatment from
Cancer
Council Victoria. You can also
call
our trusted cancer nurses on 13 11 20 for support and to learn about
our range of services for people affected by cancer.
The Victorian Cancer Registry also operates an interactive web
portal,
Data
Explorer, which provides more trends and statistics than published
here.
How common is breast cancer?
In 2024, 5490 Victorians were diagnosed with breast cancer. Of these,
there were 45 males and 5445 females, representing 0.82% and 99% of the
total Victorian breast cancer diagnoses, respectively. Currently, breast
cancer is diagnosed at a rate of 1.1 per 100,000 males and 133 per
100,000 females. The median age at diagnosis of breast cancer is 70
years in males and 61 in females. Figure 1 and 2 show the distribution
of breast cancer among Victorian females. Due to low numbers of cases
when single years are displayed, Figure 1 and 2 do not include data for
males. Accounting for 14% of all cancers diagnosed and 6.1% of all
cancer-related deaths in 2024, breast cancer was the most commonly
diagnosed cancer among females and the 38th most commonly diagnosed
cancer among males. It is the 2nd most common cause of cancer-related
deaths in Victorian females and the 44th most common cause of
cancer-related deaths in Victorian males.
Trends in breast cancer over time
For females between 1995 to 2024 the age standardised incidence rate
of breast cancer increased by an average of 0.47% per year.
Breast cancer morphology
Figure 4 provides a summary of the different types of cells
(morphology) which have caused breast cancer for males and females
combined. Most breast cancer tumours, 76%, present as breast carcinoma,
no special type.
Breast cancer subtypes
A tissue biopsy of breast cancer tissue enables the molecular makeup
of the tumour to be further examined. This is undertaken to determine
the best treatment path. Some tumours may have cells with hormone
receptors which help cancers to grow. Cancers which receive signals from
oestrogen are referred to as oestrogen receptor positive (ER+) and those
receiving progesterone signals are progesterone receptor positive (PR+)
cancers. Breast cancer tissue is also examined to assess whether the
presence of the protein human epithelial growth factor receptor 2 (HER2)
that appears on the surface of the breast cancer cells and may stimulate
cancer cells to grow. Breast cancer tissue with high levels of HER2
protein is referred to as HER2 positive (HER2+) or HER2 amplified.
Luminal tumours are hormone-positive (ER+ and/or PR+) and HER2
negative.
Non-luminal tumours are HER2+ but both ER and PR negative. Triple
negative tumours refers to breast cancer tissue which does not contain
oestrogen receptors, progresterone receptors or HER2 (TNBC). People
diagnosed with TNBC are usually treated with chemotherapy, because the
tumour does not respond to drugs specifically developed to target
oestrogen or progesterone or HER2.
Figure 5 provides a summary of
the hormone status of tumours diagnosed in 2024 among both males and
females.
Geographical variance in breast cancer by local government area
Figure 6 demonstrates variation in the estimated risk of being
diagnosed with breast cancer for females, by local government area,
relative to the Victorian average. Red shading indicates areas with
higher risk and blue shading indicates areas with lower risk relative to
Victoria.
Breast cancer in people born overseas
Figure 7 shows the standardised incidence ratios (SIRs) of breast
cancers in Australian-born Victorians compared to other major migrant
groups, over the five-year period 2019 to 2023. The highest standardised
incidence ratio (SIR) for breast cancers was 3.8 for males born in the
North America region and the lowest SIR of 0.00 was observed in males
born in the South and Central America region. The highest standardised
incidence ratio (SIR) of breast cancers was 1.1 for females born in the
UK and Ireland region and the lowest SIR of 0.74 was observed in females
born in the Southern and Central Asia region.
Breast cancer distribution by stage at diagnosis
Figure 8 shows distribution of breast cancer by stage of disease at
diagnosis in 2024. In females, Stage 1 accounted for the largest
proportion (39%) of new diagnoses and Stage 4 accounted for the lowest
proportion (4.1%) of new breast cancer diagnoses. Because of low
numbers, data are not presented for males or those where sex is not
recorded, or is recorded as indeterminate.
Breast cancer five-year relative survival
Figure 9 shows the change in 5-year survival for breast cancer among
males and females, and the 5-year survival trend for all cancers over
the same time period. It shows that 5-year relative survival has
increased for breast cancer between 1985-1989 and 2020-2024 from 72% to
93%.