The role of necroptosis in tumour suppression & the response of malignant tumour cells to anti-cancer therapy

Lead researcher

Prof Andreas Strasser, Dr Wendy Cook

Institution

Walter and Eliza Hall Institute of Medical Research

Years funded

2013-2015

Programmed cell death plays critical roles in development and cell-turnover in the adult. Defects in this process can cause cancer. We will use genetic and biochemical approaches to define the individual roles of necroptosis, a newly described cell death process, and those overlapping with apoptosis in normal development and cell-turnover as well as in cancer.

The objective of this work is to identify potential targets for therapeutic intervention in cancer.

Lay report (Final)

Funding Body

Cancer Council Victoria Research Grant

Funding

$99,730 pa for three years

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