Programmed cell death plays critical roles in development and cell-turnover in the adult. Defects in this process can cause cancer. We will use genetic and biochemical approaches to define the individual roles of necroptosis, a newly described cell death process, and those overlapping with apoptosis in normal development and cell-turnover as well as in cancer.
The objective of this work is to identify potential targets for therapeutic intervention in cancer.
Prof Andreas Strasser, Dr Wendy Cook
Cancer Council Victoria Research Grant
Walter and Eliza Hall Institute of Medical Research
$99,730 pa for three years