Regulation of signalling pathways & protein trafficking by Lgl/aPKC

Project Description

This project investigates how mutation of cell shape regulators affects protein localisation and deregulates signalling pathways. Since these cell shape regulators and the signalling pathways they control are perturbed in many cancers, this work may lead to the identification of new biomarkers and therapeutics to combat cancer.

Lay Report (Final)

Year

2013-2015

Researchers

A/Prof Helena Richardson, Dr Alexey Veraksa

Funding Body

Cancer Council Victoria Research Grant

Institution

The University of Melbourne

Funding

$100,000 pa for three years

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