Control of leukaemic blood cells

Project Description

The formation and functions of white blood cells are controlled by special chemical messengers (cytokines) that bind to the surface of blood cells. Over-responses or incorrect responses to cytokine instructions leads to leukaemia development. At present we are analysing how cells respond to their instructions and the chemicals inside the cell that determine whether the cells will respond abnormally.

Regulatory control of normal and leukaemic cells (PDF 666KB)

Year

1954 - 2014

Researchers

Professor Emeritus Don Metcalf

Institution

Divison of Cancer and Haematology, Walter and Eliza Hall Institute of Medical Research

Award / Duration

Carden Fellowship

Funding

$200,000 per annum

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