Colorectal cancer (CRC) is the second most common type of cancer in Australia. Unfortunately, only a small number of CRCs are detected in the early stages, and once CRC has spread to other parts of the body, current therapies are ineffective. We will use clinically relevant mouse models to define the contribution of necroptosis, a new programmed cell death pathway, to the initiation and progression of CRC. Our objective is to improve the development of new anti-cancer therapies for advanced CRC.
Dr James Murphy, Dr Silvia Alvarez-Diaz, A/Prof Matthias Ernst
Cancer Council Research Grant
Cell Signalling and Cell Death, The Walter and Eliza Hall Institute of Medical Research
$99,826 per annum