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Regulation of microRNAs in stomach inflammation & cancer

Project Description

Stomach cancer is the second most common cause of cancer-related deaths worldwide, and is strongly associated with the development of stomach inflammation (gastritis).

This project explores the role of a new class of “minigenes” called microRNAs in the initiation of gastritis and ultimately stomach cancer. The results will lead to a better understanding of how stomach cancer, and also other inflammation-associated cancers (e.g. colon), are triggered, which in turn has the potential to lead to the identification of new targets for early detection.