Upstream signalling in the Hippo tumour suppressor pathway

Lead researcher

A/Prof Kieran Harvey

Institution

Peter MacCallum Cancer Centre

Years funded

2014-2016

The Hippo pathway is a group of genes that works together to control the size of different organs, and is commonly mutated in human cancers. We aim to decipher how Hippo pathway proteins relay signals from the cell surface to the nucleus to instruct cells on when to grow, divide and survive. Our studies will shed light on how tissue growth is controlled, and have the potential to inform the way that we treat human cancers and tissue growth disorders.

Lay Report:

Funding Body

Cancer Council Research Grant

Funding

$100,000 per annum

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