Non-classical mineralocorticoid receptor signalling in reproductive tissues

Project Description

The receptor for the salt retaining hormone aldosterone, the mineralocorticoid receptor, is present in normal breast. Our recent large study identified a potential inhibitory role for the mineralocorticoid receptor in breast cancer. These findings raise exciting possibilities with respect to the regulation of cell growth. The proposed studies will explore this unchartered territory with a view to identifying and exploring a range of novel possible targets for the treatment of breast cancer.

Lay report:

Year

2015-2017

Researchers

Prof Peter Fuller, Dr Ann Drummond, Dr Morag Young, Prof Christine Clarke

Funding Body

Cancer Council Research Grant - Girls Night In

Institution

Hudson Institute of Medical Research

Funding

$100,000 per annum

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