Structural linkage between ligand discrimination and receptor activation by interleukin-3

Lead researcher

Dr Urmi Dhagat, Dr Sophie Broughton, Prof Michael Parker, A/Prof Louise Purton

Institution

Structural Biology, St Vincent's Institute of Medical Research

Years funded

2017-2019

This project studies the mechanism by which interleukin-3 activates abnormal signalling in leukaemic cells. Our findings will allow development of new approaches by which we could specifically target and disrupt leukaemic cell survival.

Funding Body

Cancer Council Research Grant

Funding

$99,599 in 2017, $99,199 in 2018 and $99,199 in 2019

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