Melanoma is responsible for the majority of skin cancer related deaths and its incidence is rising. Strategies to harness the body's own immune system have shown promising anti-tumour effects, however, only a group of patients shows a response. We identified a novel molecule in melanoma that may block the immune system from efficiently destroying the tumour. This application aims to understand and interfere with the immune-suppressive action of this protein to create new therapeutic options.
Dr Andreas Behren, Dr Katherine Woods, Prof Jonathan Cebon
Cancer Council Research Grant
Cancer Immunobiology, Olivia Newton-John Cancer Research Institute