A phase III trial comparing adjuvant versus salvage radiotherapy for high risk patients post radical prostatectomy

Project Description

Nearly half of cancer patients having an operation to remove the prostate will have a high risk of recurrence. Giving immediate radiotherapy to all such patients will improve cure rates but does not benefit all men and can cause significant side effects.

This study will explore whether it's safe to only give radiotherapy when there's a rising PSA after surgery, indicating active cancer. A total of 420 men from Australasia will enter this study comparing these 2 approaches.




Dr Andrew Kneebone (NSW), Dr Scott Williams (VIC), Prof Gillian Duchesne (VIC), A/Prof Richard Fisher (VIC), A/Prof Mark Frydenberg (VIC)

Funding Body

Cancer Council Research Grant


$100,000 in 2008, $98,000 in 2009, $98,000 in 2010, nil in 2011