Diagnosing stomach or oesophageal cancer

Doctors and other health professionals you may see

How stomach and oesophageal cancer is diagnosed

Further tests

‘Staging' the disease  

In their early stages, these cancers often do not cause any symptoms. This means that they are usually not diagnosed until the cancer is more advanced.

Symptoms of stomach cancer are like those of many other conditions. Signs of early stomach cancer include a painful or burning sensation in the abdomen, heartburn or indigestion (dyspepsia). If someone who is aged over 45 develops these symptoms, and they do not go away, they may need to be examined for stomach cancer.

Other symptoms can occur later, including:

  • a sense of fullness, even after a small meal
  • nausea and/or vomiting
  • loss of appetite and/or weight loss
  • swelling of the abdomen
  • unexplained tiredness or weakness
  • blood in vomit
  • black-coloured faeces.

Symptoms of oesophageal cancer include:

  • difficult or painful swallowing
  • weight loss
  • vomiting/coughing up blood.

If you have not been diagnosed with cancer and are just looking through this booklet, please be aware that many of these symptoms occur without any serious disease being present. However, if you have any of the symptoms for more than two weeks, see your doctor for a check-up.

Doctors and other health professionals you may see

Your doctor will examine you and refer you for tests to see if you have cancer. This can be a worrying and tiring time, especially if you need to have several tests.

If the tests show you have or may have cancer, your doctor will refer you to a specialist. You may have further tests and then the specialist will advise you about treatment options.

You should expect to be cared for by a team of health professionals from the relevant major fields (see list below). Ideally, your tests and treatments should be available at your hospital. This may not be possible in some non-metropolitan areas.

Specialists and other health professionals who care for people with stomach and oesophageal cancer include:

  • gastroenterologists and gastrointestinal surgeons, who diagnose and treat people with diseases of the digestive system
  • medical oncologists, who specialise in chemotherapy
  • radiation oncologists, who specialise in radiotherapy (also known as radiation therapy)
  • nurses and general practitioners, who will help you through all stages of your cancer
  • dietitians, who will recommend the best diets to follow while you are in treatment and recovery
  • social workers, physiotherapists and occupational therapists, who will advise you on support services and help you to get back to normal activities
  • palliative care physicians, who will help with the relief of symptoms.

How stomach and oesophageal cancer is diagnosed

The common tests for these cancers are described in this section. You may not have all of the tests. When the tests are done, your doctor or doctors will tell you what they have learned and suggest the best treatment for you.

Before referring you for tests, your doctor will take a full medical history and examine you. You may also have a blood test and chest x-ray to check your general health.

Endoscopy/gastroscopy

In this test, a thin, flexible ‘telescope' (called an endoscope) will be passed down your throat so that the doctor can examine your oesophagus, stomach and the upper part of your bowel.

If anything unusual is seen, the doctor can put instruments down the endoscope and remove tissue to examine under a microscope-this is called a biopsy.

You will have a sedative and a local anaesthetic to make you as comfortable as possible during the test. (Some people need to have a general anaesthetic.) You may even fall asleep. You will be asked not to eat or drink anything for a period of time before the test. Following the test, because of the sedative, you should not drive a car or operate machinery until the next day.

This test has some risks, including bleeding and a very small risk of perforation (where a hole is accidentally made in the stomach or oesophagus). A small number of people are affected (less than 0.1%). Your doctor should explain all the risks before you consent to having the procedure.

Barium swallow/upper gastrointestinal x-ray

This test is less commonly done now that endoscopy is available.

If you have this test you will drink a thick, chalky liquid called barium. This will coat the lining of your oesophagus, stomach and the first part of your bowel. You will lie down on a couch and a radiologist will take x-ray pictures of your chest and abdomen. X-rays can't pass through the coating of barium, so anything unusual will be seen.

To look for stomach cancer, you may be asked to swallow a thin tube, through which air can be pumped into your stomach. This makes the barium coating very thin, so even small abnormalities will show up. (The tube will be taken out of your throat afterwards.)

You may be slightly uncomfortable as the couch is tipped in different ways to help the barium flow through your whole stomach. The test takes about an hour. You will be asked not to eat or drink for several hours beforehand.

Endoscopic ultrasound

This is similar to having an endoscopy. It may be used for people who may have oesophageal cancer and occasionally for people who may have stomach cancer. For this test, the endoscope has a small ultrasound probe on the end. The probe releases high-frequency sound waves and then detects the sound wave echoes that bounce off tissue of the oesophageal or stomach wall. A computer translates the pattern of echoes into a picture.

This test may show whether cancer has spread into the wall of the organ, nearby tissue and to nearby lymph nodes.

Further tests

If you are diagnosed with stomach or oesophageal cancer, you may have some more tests to find out if the cancer has spread. These tests will help your doctor or doctors advise the best treatment for your cancer.

Computerised tomography (CT) scan

A CT scan is a type of x-ray that gives a two or sometimes three-dimensional (3-D) picture of organs and other structures (including any tumours) in your body. It is used to see if cancer has spread into the lymph nodes, liver, abdomen cavity or other parts of the body.

CT scans are usually done at a hospital or a radiology clinic. It usually takes 30 to 40 minutes to complete this painless test. You may be asked not to have a meal before the scan. You will have a liquid contrast before the scan, in a drink and in an injection. This dye makes your organs appear white on the scans that are taken, so anything unusual will show more clearly. 

You will be asked to lie on a table, which is moved into the CT scanner, which is large and round like a doughnut. Most people are able to go home as soon as their scan is over.

There is a small possibility of the injected dye causing an allergic reaction. You should tell your doctor if you are allergic to iodine or to contrast dyes, or if you are diabetic or have abnormal kidney function.

Ultrasound scan

In this test, sound waves are used to create a picture of your internal organs, including your liver, to see if cancer has spread.

You will uncover your abdomen and lie on a table. Once you are comfortable, a gel will be spread on the skin over the area being scanned.

A small device called a ‘transducer' will be moved across your abdomen. It makes sound waves and receives echoes. A computer makes a picture of the echoes produced when the sound waves meet something dense, like an organ or a tumour. An ultrasound scan is mainly used to see if cancer has spread to the liver.

This is painless and takes 15 to 20 minutes.

Positron emission tomography (PET) scan

This is a test that helps find out how far the tumour has advanced and whether it has spread to other parts of the body. It is often combined with a CT scan. You will be asked to not eat or drink anything before the PET scan. A small amount of radioactive material will be injected into a vein in your arm one hour before the scan. You will then be asked to lie or sit in a darkened room until the scan. For the scan, you will lie on a table and be moved through a large ring-shaped scanner. The tube may make some people feel claustrophobic. If you think you are likely to be affected in this way, please tell the treatment centre before your scan.   

Only a few centres in Victoria offer this test, so you may have to travel to have this done.

Laparoscopy

This test is for people diagnosed with stomach cancer, and sometimes for people with oesophageal cancer.

You will be admitted to hospital and will have a general anaesthetic. Through small cuts in your abdomen, the doctor will use a tube to put gas into your abdomen, then put in a thin ‘telescope' called a ‘laparoscope'. Through this, the doctor can look for small amounts of cancer that may have spread into the liver or the lining of the abdomen.

A biopsy can be taken of any unusual tissue. This may be done as a separate procedure, or as a first step before major surgery.

Bronchoscopy

This test is similar to endoscopy. A thin, lighted tube called a ‘bronchoscope' will be put into your mouth or nose and passed down your windpipe to look into the breathing passages.

You may have this test if there is concern that the oesophageal cancer has spread close to or involved the windpipe.

Bone scan

If the doctor suspects that your cancer has spread, they may order a bone scan. This can show whether cancer has spread to the bones.

A small amount of a radioactive substance will be injected into a vein. This travels through the body and collects in bone, especially where there is unusual growth. A scanner will then measure the radioactivity in these areas.

‘Staging' the disease

The tests described on previous pages show whether you have cancer and some can also show whether it has spread. The cancer may have spread into blood vessels or lymph nodes near the stomach or oesophagus, or into organs further away, like the liver. This is called metastasis. Knowing if and how far the cancer has spread is called 'staging' the disease. Staging helps your doctor to work out the best treatment for you.

‘Staging' is a way of describing whether a cancer has spread, and if so, how far. Stage 1 means it has not spread; Stage 4 means it has spread to distant organs such as the liver or lungs.

The staging system used for stomach and oesophageal cancer is known as the ‘TNM system' (T = tumour, N = lymph nodes, M = metastases).

  • T followed by a number between 1 and 4 shows how far the tumour has spread through the wall of the stomach or oesophagus. T1 shows the tumour is only in the mucosa on the inside of the stomach or oesophagus. A higher number after the T (for example, T3 or T4) means it has spread further, for example, to the outer layers of the stomach or deeper into the lining of the oesophagus, or to nearby organs.
  • N followed by 0 means that there is no spread to lymph nodes near the tumour. N followed by 1 means there is spread to nearby lymph nodes. The small letters after 1 (eg 1a, 1b, 1c) refer to how many of the lymph nodes are involved
  • M followed by 0 means there is no distant metastasis; M1 means there is distant metastasis. Distant metastasis means that there is evidence the cancer has spread away from the area in and around the stomach or oesophagus, for example, to the liver or other organs.

Doctors combine this information to determine the stage of the cancer, from Stage 1 to Stage 4. For example, a stomach cancer staged as T3, N1, M0 (tumour spread through the stomach wall, some lymph nodes affected, no metastasis) is a Stage 3 stomach cancer.

Ask your doctor to explain the stage of your cancer in a way you can understand. This will help you to choose the best treatment for your situation.

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Updated February 2008

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Updated: 08 Aug, 2008